… Immunogenicity was primarily assessed by serum BT50. … antibody-secreting cell (ASC)
frequency, and B cell phenotyping. … evaluated safety and immunogenicity of a rAd5-based oral …

… evaluated in Bangladeshi volunteers. To enable analysis of antibody responses against
multiple vaccine … assay for analysis of intestine-derived antibody-secreting cell responses using …

… Evaluation of the safety and immunogenicity of the oral inactivated multivalent … optimal for
assessing circulating antibody-secreting cell or ALS responses after oral vaccination, with only …

… and infants can be used to evaluate vaccine specific intestinal responses induced by … well
tolerated and immunogenic in a placebo-controlled double-blind phase I trial in healthy adults …

… processed to detect serum antibodies, and to quantify antibody secreting cells (ASCs) by
ELISPOT (Fig. 1). Peripheral blood mononuclear cells (PBMCs) were isolated from whole blood …

… of cholera-specific antibody secreting cells, markers of mucosal immunity, following vaccination
with BivWC among a population … Among evaluations of immunogenicity, the detection of …

… oral vaccine remains to be fully elucidated, the best correlate identified in this study was the
induction of antibody-secreting cells … post-hoc analysis of this study suggests the oral vaccine …

… that analysis of antibody-secreting cell responses after booster vaccination may be a useful
approach to evaluate … We have recently tested the safety and immunogenicity of a novel oral …

… , well tolerated and immunogenic in a vaccine dose-dependent … tool to evaluate mucosal
responses to oral vaccination, an … We realize that the number of antibody secreting cells is not …

… immunity, which has been shown to correlate well with the transient appearance of LPS-specific
IgA antibody-secreting cells (ASC) in the peripheral blood (36). In the SC602 Shigella …